pachytene

Positions Available

  1. Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, Yanowitz JL, Buszczak M. 2020. GCNA Preserves Genome Integrity and Fertility Across Species. Dev Cell. Jan 6;52(1):38-52.e10. doi: 10.1016/j.devcel.2019.11.007. Epub 2019 Dec 12. PubMed Abstract
  2. Amrit FRG, Naim N, Ratnappan R, Loose J, Mason C, Steenberge L, McClendon BT, Wang G, Driscoll M, Yanowitz JL, Ghazi A. 2019. The Longevity-Promoting Factor, TCER-1, Widely Represses Stress Resistance and Innate Immunity. Nat Commun. Jul 17;10(1):3042. doi: 10.1038/s41467-019-10759-z. PubMed Abstract
  3. Li, W. and Yanowitz JL. 2019. ATM and ATR Influence Meiotic Crossover Formation Through Antagonistic and Overlapping Functions in Caenorhabditis elegans. Genetics. 212(2):431-443. doi: 10.1534/genetics.119.302193. Epub 2019 Apr 23. PubMed Abstract
  4. Yang B, Xu X, Russell L, Sullenberger MT, Yanowitz JL and Maine EM. 2019. A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line. PLOS Genetics. Feb 22;15(2):e1007992. doi: 10.1371/journal.pgen.1007992. PubMed Abstract
  5. Macaisne N, Kessler Z and Yanowitz JL. 2018. Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization. Genetics. 210(3):843-856. doi: 10.1534/genetics.118.301402. PubMed Abstract
  6. Ahuja, JS, Sandhu R, Mainpal E, Lawson C, Henley H, Hunt PA, Yanowitz JL, Borner GV. 2017. Control of meiotic pairing and recombination by chromosomally tethered 26S proteasome. Science 355(6323): 408-411. doi: 10.1126/science.aaf4778. http://science.sciencemag.org/content/355/6323/408.long PubMed Abstract
  7. Hillers K, Jantsch V, Martinez-Perez E, and Yanowitz JL. 2017. Meiosis. Wormbook. May 4;2017:1-43. doi: 10.1895/wormbook.1.178.1. PubMed Abstract
  8. McClendon TB, Mainpal R, AMrit FR, Krause MW, Ghazi A, Yanowitz JL. 2016. X chromosome crossover formation and genome stability in Caenorhabditis elegans are independently regulated by xnd-1. G3(Bethesday) 6(12):3913-3925. doi: 10.1534/g3.116.035725. PubMed Abstract
  9. Machovina T, Mainpal R, Daryabeigi A, McGovern O, Paouneskou D, Labella S, Zetka M, Jantsch V, and Yanowitz JL. 2016. A surveillance system ensures crossover formation in C. elegans. Current Biology 26(21):2873-2884. doi: 10.1016/j.cub.2016.09.007. PubMed Abstract
  10. Mainpal R and Yanowitz JL. 2016. A twist of fate: how a meiotic protein is providing new perspectives on germ cell development. Solicited manuscript, Worm, 5(2):e1175259. doi: 10.1080/21624054.2016.1175259.PubMed Abstract
  11. Mateo A, Kessler ZK, Jolliffe K, McGovern O, Yu B, Nicolucci, A, Yanowitz JL*, and Derry WB*. 2016. The p53-like protein CEP-1 is required for meiotic fidelity in C. elegans. Current Biology, 26(9):1148-58. doi: 10.1016/ j.cub.2016.03.036. *co-corresponding authors. PubMed Abstract
  12. McClendon TB, Sullivan MR, Bernstein KA*, Yanowitz JL*. 2016. Promotion of homologous recombination by SWS-1 in complex with RAD-51 paralogs in Caenorhabditis elegans. Genetics, advanced online publication, March 2, 2016. doi: 10.1534/genetics.115.185827. *co-corresponding authors. PubMed Abstract
  13. Amrit FRG, Steenkiste AM, Ratnappan R, Chen S-W, McClendon TB, Kostka D, Yanowitz J, Olsen CP and Ghazi A. 2016. DAF-16 and TCER-1 facilitate adaptation to germline loss by restoring lipid homeostasis and repressing reproductive physiology in C. elegans. PLoS Genetics 12(2):e1005788. doi: 10.1371/journal.pgen.1005788. PubMed Abstract
  14. Mainpal R, Nance J, and Yanowitz JL. 2015. A germ cell determinant reveals parallel pathways for germ line development in Caenorhabditis elegans. Development Sept 22 pii: dev.125732 PMID: 26395476. PubMed Abstract
  15. Chung G, Rose AM, Petalcorin MI, Martin JS, Kessler Z, Sanchez-Pulido L, Ponting CP, Yanowitz JL*, Boulton SJ*. 2015 REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand formation in ,Caenorhabditis elegans. Genes and Development Sep 15;29(18):1969-79. PMID: 26385965. *co-corresponding authors. PubMed Abstract
  16. Ghazi A*, Yanowitz J*, Silverman GA*. 2014 Expanding the C. elegans toolbox into a toolshed. Methods. Aug 1;68(3):379-80. PMID: 25064639 *co-corresponding authors. PubMed Abstract
  17. Zevian S and Yanowitz J. 2014. Methodological considerations for heat shock of the nematode Caenorhabditis elegans. Methods. Aug 1;68(3):450-7. Epub 2014 Apr 26. PMCID:PMC4112136. PubMed Abstract
  18. Kessler Z and Yanowitz J. 2014. Methodological considerations for mutagen exposure in C. elegans. Methods. Aug 1;68(3):441-9. Epub 2014 Apr 21. PMID: 24768858. PubMed Abstract
  19. Meneely PM, McGovern OL, Heinis FI, and Yanowitz J.  2012. Crossover distribution and frequency is regulated by him-5 in C. elegans. Genetics Apr;190(4):1251-66. (Epub ahead of print).
  20. Graham PL, Yanowitz JL, Penn JKM, Desphpande G, Schedl P. 2011.The translation initiation factor eif4e regulates the Sex-Specific expression of the master switch gene Sxl in Drosophila melanogaster. PLoS Genetics 7(7): e1002185.
  21. Vogel BE, Wagner C, Paterson JM, Xu X, and Yanowitz J. 2011. An extracellular matrix protein prevents cytokinesis failure and aneuploidy in the C. elegans germline. Cell Cycle 10(12): 1916–1920.
  22. Wagner, C., Kuervers, L., Baillie, D., and Yanowitz, J. 2010. xnd-1 regulates the global recombination landscape in C. elegans.  Nature 467: 839-843.
  23. Yanowitz, J. 2010. Meiosis: Making a Break for It. Current Opinion in Cell Biology, 22(6):744-51.
  24. Lim, J.G., Stine, R.R., and Yanowitz, J. 2008. Domain-specific regulation of recombination in C. elegans in response to temperature age, and sex. Genetics, Oct;180(2): 715-26.
  25. Yanowitz, J. 2008. Genome integrity is regulated by the C. elegans Rad51D homolog, rfs-1. Genetics, May;179(1): 249-62. PubMed Abstract
  26. Hochheiser, H. and Yanowitz, J. 2007. If I only had a brain: exploring mouse brain images in the Allen Brain Atlas. Biol. Cell, Jul;99(7): 403-9. PubMed Abstract
  27. Ward, J.D., Barber, L.J., Petalcorin, M.I.R., Yanowitz, J., and Boulton, S.J. 2007. Replication blocking lesions present a unique substrate for homologous recombination. Embo J., Jul;26(14): 3384-96. PubMed Abstract
  28. Foehr, M.L., Lindy, A.S., Fairbank, R.C., Amin, N.M., Xu, M., Yanowitz, J., Fire, A.Z., and Liu, J. 2006. An antagonistic role for the C. elegans Schnurri homolog SMA-9 in modulating TGFbeta signaling during mesodermal patterning. Development, Aug;133(15): 2887-96.PubMed Abstract
  29. Yanowitz J. and Fire, A.Z. 2005. Cyclin D involvement demarcates a late transition in C. elegans embryogenesis. Dev Biol., Mar,1;279(1): 244-51.PubMed Abstract
  30. Yanowitz J., Shakir, M.A., Hedgecock, E., Fire, A.Z. and Lundquist, E.A. 2004. UNC-39, the C. elegans homolog of the human myotonic dystrophy-associated homeodomain protein Six5, regulates cell motility and differentiation. Dev Biol., Aug,15;272(2): 389-402. PubMed Abstract
  31. Greenberg, T., Yanowitz, J, and Schedl, P. 2004. The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the MSL complex chromatin entry site at 12DE. Genetics, Jan;166(1): 279-89. PubMed Abstract
  32. Deshpande G., Calhoun G. , Yanowitz J., and Schedl P. 1999. Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline. Cell, Oct,29;99(3):271-81.PubMed Abstract
  33. Yanowitz J., Deshpande G., Calhoun G., and Schedl P. 1999. An N- terminal truncation uncouples the sex-transforming and dosage compensation functions of Sex-lethal. Mol Cell Biol., Apr;19(4): 3018-28.PubMed Abstract
  34. Hanish J., Yanowitz J., and de Lange, T. 1994. Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci USA. Sept,13;91(19):8861-65. PubMed Abstract